diff --git a/src/crypto/poly1305.h b/src/crypto/poly1305.h
index 39b69e1cd4f..080543ffeee 100644
--- a/src/crypto/poly1305.h
+++ b/src/crypto/poly1305.h
@@ -5,6 +5,9 @@
 #ifndef BITCOIN_CRYPTO_POLY1305_H
 #define BITCOIN_CRYPTO_POLY1305_H
 
+#include <span.h>
+
+#include <cassert>
 #include <cstdlib>
 #include <stdint.h>
 
@@ -32,6 +35,40 @@ void poly1305_finish(poly1305_context *st, unsigned char mac[16]) noexcept;
 
 }  // namespace poly1305_donna
 
+/** C++ wrapper with std::byte Span interface around poly1305_donna code. */
+class Poly1305
+{
+    poly1305_donna::poly1305_context m_ctx;
+
+public:
+    /** Length of the output produced by Finalize(). */
+    static constexpr unsigned TAGLEN = POLY1305_TAGLEN;
+
+    /** Length of the keys expected by the constructor. */
+    static constexpr unsigned KEYLEN = POLY1305_KEYLEN;
+
+    /** Construct a Poly1305 object with a given 32-byte key. */
+    Poly1305(Span<const std::byte> key) noexcept
+    {
+        assert(key.size() == KEYLEN);
+        poly1305_donna::poly1305_init(&m_ctx, UCharCast(key.data()));
+    }
+
+    /** Process message bytes. */
+    Poly1305& Update(Span<const std::byte> msg) noexcept
+    {
+        poly1305_donna::poly1305_update(&m_ctx, UCharCast(msg.data()), msg.size());
+        return *this;
+    }
+
+    /** Write authentication tag to 16-byte out. */
+    void Finalize(Span<std::byte> out) noexcept
+    {
+        assert(out.size() == TAGLEN);
+        poly1305_donna::poly1305_finish(&m_ctx, UCharCast(out.data()));
+    }
+};
+
 void poly1305_auth(unsigned char out[POLY1305_TAGLEN], const unsigned char *m, size_t inlen,
     const unsigned char key[POLY1305_KEYLEN]);
 
diff --git a/src/test/crypto_tests.cpp b/src/test/crypto_tests.cpp
index b29df832b4f..85494e1b208 100644
--- a/src/test/crypto_tests.cpp
+++ b/src/test/crypto_tests.cpp
@@ -191,6 +191,22 @@ static void TestPoly1305(const std::string &hexmessage, const std::string &hexke
     tagres.resize(POLY1305_TAGLEN);
     poly1305_auth(tagres.data(), m.data(), m.size(), key.data());
     BOOST_CHECK(tag == tagres);
+
+    // Test incremental interface
+    for (int splits = 0; splits < 10; ++splits) {
+        for (int iter = 0; iter < 10; ++iter) {
+            auto data = MakeByteSpan(m);
+            Poly1305 poly1305{MakeByteSpan(key)};
+            for (int chunk = 0; chunk < splits; ++chunk) {
+                size_t now = InsecureRandRange(data.size() + 1);
+                poly1305.Update(data.first(now));
+                data = data.subspan(now);
+            }
+            tagres.assign(POLY1305_TAGLEN, 0);
+            poly1305.Update(data).Finalize(MakeWritableByteSpan(tagres));
+            BOOST_CHECK(tag == tagres);
+        }
+    }
 }
 
 static void TestHKDF_SHA256_32(const std::string &ikm_hex, const std::string &salt_hex, const std::string &info_hex, const std::string &okm_check_hex) {
diff --git a/src/test/fuzz/crypto_poly1305.cpp b/src/test/fuzz/crypto_poly1305.cpp
index ac555ed68ce..94a7ed06e91 100644
--- a/src/test/fuzz/crypto_poly1305.cpp
+++ b/src/test/fuzz/crypto_poly1305.cpp
@@ -20,3 +20,34 @@ FUZZ_TARGET(crypto_poly1305)
     std::vector<uint8_t> tag_out(POLY1305_TAGLEN);
     poly1305_auth(tag_out.data(), in.data(), in.size(), key.data());
 }
+
+
+FUZZ_TARGET(crypto_poly1305_split)
+{
+    FuzzedDataProvider provider{buffer.data(), buffer.size()};
+
+    // Read key and instantiate two Poly1305 objects with it.
+    auto key = provider.ConsumeBytes<std::byte>(Poly1305::KEYLEN);
+    key.resize(Poly1305::KEYLEN);
+    Poly1305 poly_full{key}, poly_split{key};
+
+    // Vector that holds all bytes processed so far.
+    std::vector<std::byte> total_input;
+
+    // Process input in pieces.
+    LIMITED_WHILE(provider.remaining_bytes(), 100) {
+        auto in = provider.ConsumeRandomLengthString();
+        poly_split.Update(MakeByteSpan(in));
+        // Update total_input to match what was processed.
+        total_input.insert(total_input.end(), MakeByteSpan(in).begin(), MakeByteSpan(in).end());
+    }
+
+    // Process entire input at once.
+    poly_full.Update(total_input);
+
+    // Verify both agree.
+    std::array<std::byte, Poly1305::TAGLEN> tag_split, tag_full;
+    poly_split.Finalize(tag_split);
+    poly_full.Finalize(tag_full);
+    assert(tag_full == tag_split);
+}