diff --git a/contrib/guix/manifest.scm b/contrib/guix/manifest.scm
index fd0e2e6a83e..7fe9430c8d7 100644
--- a/contrib/guix/manifest.scm
+++ b/contrib/guix/manifest.scm
@@ -440,6 +440,7 @@ inspecting signatures in Mach-O binaries.")
                   "--enable-host-bind-now=yes",
                   "--enable-standard-branch-protection=yes",
                   "--enable-cet=yes",
+                  "--enable-gprofng=no",
                   "--disable-gcov",
                   "--disable-libgomp",
                   "--disable-libquadmath",