diff --git a/test/functional/interface_usdt_coinselection.py b/test/functional/interface_usdt_coinselection.py
index 11bb7fa12ff..ffb97fb8d18 100755
--- a/test/functional/interface_usdt_coinselection.py
+++ b/test/functional/interface_usdt_coinselection.py
@@ -117,6 +117,7 @@ class CoinSelectionTracepointTest(BitcoinTestFramework):
         self.skip_if_no_python_bcc()
         self.skip_if_no_bpf_permissions()
         self.skip_if_no_wallet()
+        self.skip_if_running_under_valgrind()
 
     def get_tracepoints(self, expected_types):
         events = []
diff --git a/test/functional/interface_usdt_mempool.py b/test/functional/interface_usdt_mempool.py
index c356d0f010c..0ffae66752b 100755
--- a/test/functional/interface_usdt_mempool.py
+++ b/test/functional/interface_usdt_mempool.py
@@ -158,6 +158,7 @@ class MempoolTracepointTest(BitcoinTestFramework):
         self.skip_if_no_bitcoind_tracepoints()
         self.skip_if_no_python_bcc()
         self.skip_if_no_bpf_permissions()
+        self.skip_if_running_under_valgrind()
 
     def added_test(self):
         """Add a transaction to the mempool and make sure the tracepoint returns
diff --git a/test/functional/interface_usdt_net.py b/test/functional/interface_usdt_net.py
index d9d7ee12e09..de481133aae 100755
--- a/test/functional/interface_usdt_net.py
+++ b/test/functional/interface_usdt_net.py
@@ -254,6 +254,7 @@ class NetTracepointTest(BitcoinTestFramework):
         self.skip_if_no_bitcoind_tracepoints()
         self.skip_if_no_python_bcc()
         self.skip_if_no_bpf_permissions()
+        self.skip_if_running_under_valgrind()
 
     def run_test(self):
         self.p2p_message_tracepoint_test()
diff --git a/test/functional/interface_usdt_utxocache.py b/test/functional/interface_usdt_utxocache.py
index b30d0e88ac7..fe7f7e3adb6 100755
--- a/test/functional/interface_usdt_utxocache.py
+++ b/test/functional/interface_usdt_utxocache.py
@@ -150,6 +150,7 @@ class UTXOCacheTracepointTest(BitcoinTestFramework):
         self.skip_if_no_bitcoind_tracepoints()
         self.skip_if_no_python_bcc()
         self.skip_if_no_bpf_permissions()
+        self.skip_if_running_under_valgrind()
 
     def run_test(self):
         self.wallet = MiniWallet(self.nodes[0])
diff --git a/test/functional/interface_usdt_validation.py b/test/functional/interface_usdt_validation.py
index f7d518d8930..f7e2cb84e5f 100755
--- a/test/functional/interface_usdt_validation.py
+++ b/test/functional/interface_usdt_validation.py
@@ -64,6 +64,7 @@ class ValidationTracepointTest(BitcoinTestFramework):
         self.skip_if_no_bitcoind_tracepoints()
         self.skip_if_no_python_bcc()
         self.skip_if_no_bpf_permissions()
+        self.skip_if_running_under_valgrind()
 
     def run_test(self):
         # Tests the validation:block_connected tracepoint by generating blocks
diff --git a/test/functional/test_framework/test_framework.py b/test/functional/test_framework/test_framework.py
index 75a0cb6f112..f11554fe76e 100755
--- a/test/functional/test_framework/test_framework.py
+++ b/test/functional/test_framework/test_framework.py
@@ -1016,6 +1016,11 @@ class BitcoinTestFramework(metaclass=BitcoinTestMetaClass):
         if not self.is_external_signer_compiled():
             raise SkipTest("external signer support has not been compiled.")
 
+    def skip_if_running_under_valgrind(self):
+        """Skip the running test if Valgrind is being used."""
+        if self.options.valgrind:
+            raise SkipTest("This test is not compatible with Valgrind.")
+
     def is_cli_compiled(self):
         """Checks whether bitcoin-cli was compiled."""
         return self.config["components"].getboolean("ENABLE_CLI")