diff --git a/src/init.cpp b/src/init.cpp
index bc457e786ca..1984ce17991 100644
--- a/src/init.cpp
+++ b/src/init.cpp
@@ -547,7 +547,7 @@ void SetupServerArgs(ArgsManager& argsman, bool can_listen_ipc)
                    ArgsManager::ALLOW_ANY, OptionsCategory::OPTIONS);
     argsman.AddArg("-pid=<file>", strprintf("Specify pid file. Relative paths will be prefixed by a net-specific datadir location. (default: %s)", BITCOIN_PID_FILENAME), ArgsManager::ALLOW_ANY, OptionsCategory::OPTIONS);
     argsman.AddArg("-prune=<n>", strprintf("Reduce storage requirements by enabling pruning (deleting) of old blocks. This allows the pruneblockchain RPC to be called to delete specific blocks and enables automatic pruning of old blocks if a target size in MiB is provided. This mode is incompatible with -txindex. "
-            "Warning: Reverting this setting requires re-downloading the entire blockchain. "
+            "Warning: Reverting this setting requires re-downloading the entire blockchain. Wallets and indexes should be loaded at startup and kept active while pruning is enabled so they stay synchronized before old block data is deleted; wallets or indexes that fall behind pruned data may require a reindex. "
             "(default: 0 = disable pruning blocks, 1 = allow manual pruning via RPC, >=%u = automatically prune block files to stay under the specified target size in MiB)", MIN_DISK_SPACE_FOR_BLOCK_FILES / 1_MiB), ArgsManager::ALLOW_ANY, OptionsCategory::OPTIONS);
     argsman.AddArg("-reindex", "If enabled, wipe chain state and block index, and rebuild them from blk*.dat files on disk. Also wipe and rebuild other optional indexes that are active. If an assumeutxo snapshot was loaded, its chainstate will be wiped as well. The snapshot can then be reloaded via RPC.", ArgsManager::ALLOW_ANY, OptionsCategory::OPTIONS);
     argsman.AddArg("-reindex-chainstate", "If enabled, wipe chain state, and rebuild it from blk*.dat files on disk. If an assumeutxo snapshot was loaded, its chainstate will be wiped as well. The snapshot can then be reloaded via RPC.", ArgsManager::ALLOW_ANY, OptionsCategory::OPTIONS);
diff --git a/src/qt/forms/optionsdialog.ui b/src/qt/forms/optionsdialog.ui
index 9ab6b124e0d..ce410bbfb03 100644
--- a/src/qt/forms/optionsdialog.ui
+++ b/src/qt/forms/optionsdialog.ui
@@ -55,7 +55,7 @@
          <item>
           <widget class="QCheckBox" name="prune">
            <property name="toolTip">
-            <string>Enabling pruning significantly reduces the disk space required to store transactions. All blocks are still fully validated. Reverting this setting requires re-downloading the entire blockchain.</string>
+            <string>Enabling pruning significantly reduces the disk space required to store transactions. All blocks are still fully validated. Wallets should be loaded at startup and kept active while pruning is enabled so they stay synchronized before old block data is deleted; wallets that fall behind pruned data may require a reindex. Reverting this setting requires re-downloading the entire blockchain.</string>
            </property>
            <property name="text">
             <string>Prune &amp;block storage to</string>