diff --git a/depends/Makefile b/depends/Makefile
index fde108d2c2c..c377187b50a 100644
--- a/depends/Makefile
+++ b/depends/Makefile
@@ -49,7 +49,7 @@ FALLBACK_DOWNLOAD_PATH ?= https://bitcoincore.org/depends-sources
 C_STANDARD ?= c11
 CXX_STANDARD ?= c++20
 
-BUILD = $(shell ./config.guess)
+BUILD = $(shell unset CC && ./config.guess)
 PATCHES_PATH = $(BASEDIR)/patches
 BASEDIR = $(CURDIR)
 HASH_LENGTH:=11