diff --git a/contrib/guix/libexec/build.sh b/contrib/guix/libexec/build.sh
index 092f934cd8d..51354273efa 100755
--- a/contrib/guix/libexec/build.sh
+++ b/contrib/guix/libexec/build.sh
@@ -272,10 +272,6 @@ mkdir -p "$DISTSRC"
     # Install built Bitcoin Core to $INSTALLPATH
     case "$HOST" in
         *darwin*)
-            # This workaround can be dropped for CMake >= 3.27.
-            # See the upstream commit 689616785f76acd844fd448c51c5b2a0711aafa2.
-            find build -name 'cmake_install.cmake' -exec sed -i 's| -u -r | |g' {} +
-
             cmake --install build --strip --prefix "${INSTALLPATH}" ${V:+--verbose}
             ;;
         *)