diff --git a/src/components/ChatViewer.tsx b/src/components/ChatViewer.tsx
index ff2a343..e5158e3 100644
--- a/src/components/ChatViewer.tsx
+++ b/src/components/ChatViewer.tsx
@@ -69,6 +69,8 @@ import {
   TooltipTrigger,
 } from "./ui/tooltip";
 import { useBlossomUpload } from "@/hooks/useBlossomUpload";
+import { getKindIcon } from "@/constants/kinds";
+import { getEventDisplayTitle } from "@/lib/event-title";
 
 interface ChatViewerProps {
   protocol: ChatProtocol;
@@ -831,6 +833,8 @@ export function ChatViewer({
   const handleNipClick = useCallback(() => {
     if (conversation?.protocol === "nip-10") {
       addWindow("nip", { number: 10 });
+    } else if (conversation?.protocol === "nip-22") {
+      addWindow("nip", { number: 22 });
     } else if (conversation?.protocol === "nip-29") {
       addWindow("nip", { number: 29 });
     } else if (conversation?.protocol === "nip-53") {
@@ -906,6 +910,30 @@ export function ChatViewer({
     liveActivity?.hostPubkey,
   ]);
 
+  // Get root event for NIP-10 and NIP-22 to build custom title
+  // Must be called before any early returns (React Hooks rules)
+  const rootEventId =
+    (protocol === "nip-10" || protocol === "nip-22") && conversation
+      ? conversation.metadata?.rootEventId ||
+        conversation.metadata?.providedEventId
+      : undefined;
+
+  const rootEvent = use$(
+    () => (rootEventId ? eventStore.event(rootEventId) : undefined),
+    [rootEventId],
+  );
+
+  // Compute custom title for thread-based protocols (NIP-10, NIP-22)
+  const threadTitle = useMemo(() => {
+    if ((protocol !== "nip-10" && protocol !== "nip-22") || !rootEvent) {
+      return null;
+    }
+
+    const kindIcon = getKindIcon(rootEvent.kind);
+    const eventTitle = getEventDisplayTitle(rootEvent);
+    return { kindIcon, author: rootEvent.pubkey, eventTitle };
+  }, [protocol, rootEvent]);
+
   // Handle loading state
   if (!conversationResult || conversationResult.status === "loading") {
     return (
@@ -951,10 +979,28 @@ export function ChatViewer({
               <Tooltip open={tooltipOpen} onOpenChange={setTooltipOpen}>
                 <TooltipTrigger asChild>
                   <button
-                    className="text-sm font-semibold truncate cursor-help text-left"
+                    className="text-sm font-semibold truncate cursor-help text-left flex items-center gap-1.5 min-w-0"
                     onClick={() => setTooltipOpen(!tooltipOpen)}
                   >
-                    {customTitle || conversation.title}
+                    {threadTitle ? (
+                      <>
+                        {(() => {
+                          const KindIcon = threadTitle.kindIcon;
+                          return KindIcon ? (
+                            <KindIcon className="size-4 flex-shrink-0" />
+                          ) : null;
+                        })()}
+                        <UserName
+                          pubkey={threadTitle.author}
+                          className="text-sm font-semibold flex-shrink-0"
+                        />
+                        <span className="truncate">
+                          {threadTitle.eventTitle}
+                        </span>
+                      </>
+                    ) : (
+                      customTitle || conversation.title
+                    )}
                   </button>
                 </TooltipTrigger>
                 <TooltipContent
@@ -988,7 +1034,9 @@ export function ChatViewer({
                     )}
                     {/* Protocol Type - Clickable */}
                     <div className="flex items-center gap-1.5 text-xs">
-                      {(conversation.type === "group" ||
+                      {(conversation.protocol === "nip-10" ||
+                        conversation.protocol === "nip-22" ||
+                        conversation.type === "group" ||
                         conversation.type === "live-chat") && (
                         <button
                           onClick={(e) => {
@@ -1000,11 +1048,14 @@ export function ChatViewer({
                           {conversation.protocol.toUpperCase()}
                         </button>
                       )}
-                      {(conversation.type === "group" ||
+                      {(conversation.protocol === "nip-10" ||
+                        conversation.protocol === "nip-22" ||
+                        conversation.type === "group" ||
                         conversation.type === "live-chat") && (
                         <span className="opacity-60">•</span>
                       )}
-                      {conversation.protocol === "nip-10" ? (
+                      {conversation.protocol === "nip-10" ||
+                      conversation.protocol === "nip-22" ? (
                         <span className="flex items-center gap-1 opacity-80">
                           <FileText className="size-3" />
                           Thread
@@ -1057,7 +1108,9 @@ export function ChatViewer({
           <div className="flex items-center gap-2 text-xs text-muted-foreground p-1">
             <MembersDropdown participants={derivedParticipants} />
             <RelaysDropdown conversation={conversation} />
-            {(conversation.type === "group" ||
+            {(conversation.protocol === "nip-10" ||
+              conversation.protocol === "nip-22" ||
+              conversation.type === "group" ||
               conversation.type === "live-chat") && (
               <button
                 onClick={handleNipClick}
@@ -1083,7 +1136,8 @@ export function ChatViewer({
               Header: () =>
                 hasMore &&
                 conversationResult.status === "success" &&
-                protocol !== "nip-10" ? (
+                protocol !== "nip-10" &&
+                protocol !== "nip-22" ? (
                   <div className="flex justify-center py-2">
                     <Button
                       onClick={handleLoadOlder}
diff --git a/src/lib/chat/adapters/nip-22-adapter.ts b/src/lib/chat/adapters/nip-22-adapter.ts
index 74a3465..425aaaa 100644
--- a/src/lib/chat/adapters/nip-22-adapter.ts
+++ b/src/lib/chat/adapters/nip-22-adapter.ts
@@ -22,8 +22,7 @@ import pool from "@/services/relay-pool";
 import { publishEventToRelays } from "@/services/hub";
 import accountManager from "@/services/accounts";
 import { AGGREGATOR_RELAYS } from "@/services/loaders";
-import { mergeRelaySets } from "applesauce-core/helpers";
-import { getOutboxes } from "applesauce-core/helpers/mailboxes";
+import { mergeRelaySets, getOutboxes } from "applesauce-core/helpers";
 import {
   getEventPointerFromETag,
   parseReplaceableAddress,
@@ -170,6 +169,7 @@ export class Nip22Adapter extends ChatProtocolAdapter {
         const fetchedRoot = await this.fetchEventByPointer(
           eventPointer,
           relayHints,
+          providedEvent, // Pass comment event for relay hint extraction
         );
         if (!fetchedRoot) {
           throw new Error("Comment root not found");
@@ -192,6 +192,7 @@ export class Nip22Adapter extends ChatProtocolAdapter {
         const fetchedRoot = await this.fetchAddressableEvent(
           addressPointer,
           relayHints,
+          providedEvent, // Pass comment event for relay hint extraction
         );
         if (!fetchedRoot) {
           throw new Error("Comment root not found");
@@ -868,22 +869,95 @@ export class Nip22Adapter extends ChatProtocolAdapter {
   }
 
   /**
-   * Helper: Fetch event by EventPointer
+   * Helper: Extract relay hints from comment event tags
+   * NIP-22 comments (kind 1111) may have relay hints in A/E tags
+   */
+  private extractRelayHintsFromComment(
+    comment: NostrEvent,
+    targetEventId?: string,
+    targetCoordinate?: string,
+  ): string[] {
+    const relays: string[] = [];
+
+    // Look for A-tag (addressable root) with relay hint
+    if (targetCoordinate) {
+      for (const tag of comment.tags) {
+        if (
+          (tag[0] === "A" || tag[0] === "a") &&
+          tag[1] === targetCoordinate &&
+          tag[2]
+        ) {
+          relays.push(tag[2]);
+        }
+      }
+    }
+
+    // Look for E-tag (regular event root) with relay hint
+    if (targetEventId) {
+      for (const tag of comment.tags) {
+        if (
+          (tag[0] === "E" || tag[0] === "e") &&
+          tag[1] === targetEventId &&
+          tag[2]
+        ) {
+          relays.push(tag[2]);
+        }
+      }
+    }
+
+    return relays;
+  }
+
+  /**
+   * Helper: Fetch event by EventPointer with improved relay selection
+   * Uses: relay hints from pointer, relay hints from comment tags, author's outbox relays
    */
   private async fetchEventByPointer(
     pointer: EventPointer,
     additionalHints: string[] = [],
+    commentEvent?: NostrEvent,
   ): Promise<NostrEvent | null> {
-    const relayHints = mergeRelaySets(pointer.relays || [], additionalHints);
-    return this.fetchEvent({ id: pointer.id, kind: pointer.kind }, relayHints);
+    // Merge relay hints from multiple sources
+    const pointerHints = pointer.relays || [];
+    const commentHints = commentEvent
+      ? this.extractRelayHintsFromComment(commentEvent, pointer.id)
+      : [];
+
+    // Get author's outbox relays if we know the author
+    let authorOutbox: string[] = [];
+    if (pointer.author) {
+      try {
+        const relayListEvent = await firstValueFrom(
+          eventStore.replaceable(10002, pointer.author, ""),
+          { defaultValue: undefined },
+        );
+        if (relayListEvent) {
+          authorOutbox = getOutboxes(relayListEvent);
+        }
+      } catch {
+        // Ignore errors fetching relay list
+      }
+    }
+
+    // Merge all hints (prioritize pointer hints, then comment hints, then author outbox)
+    const allHints = mergeRelaySets(
+      pointerHints,
+      commentHints,
+      authorOutbox.slice(0, 3), // Limit outbox to 3 relays
+      additionalHints,
+    );
+
+    return this.fetchEvent({ id: pointer.id, kind: pointer.kind }, allHints);
   }
 
   /**
-   * Helper: Fetch addressable event by AddressPointer
+   * Helper: Fetch addressable event by AddressPointer with improved relay selection
+   * Uses: relay hints from pointer, relay hints from comment tags, author's outbox relays
    */
   private async fetchAddressableEvent(
     pointer: AddressPointer,
     additionalHints: string[] = [],
+    commentEvent?: NostrEvent,
   ): Promise<NostrEvent | null> {
     const { kind, pubkey, identifier } = pointer;
 
@@ -894,10 +968,37 @@ export class Nip22Adapter extends ChatProtocolAdapter {
     );
     if (cached) return cached;
 
-    // Not in store - fetch from relays
-    const relayHints = mergeRelaySets(pointer.relays || [], additionalHints);
+    // Merge relay hints from multiple sources
+    const pointerHints = pointer.relays || [];
+    const coordinate = `${kind}:${pubkey}:${identifier}`;
+    const commentHints = commentEvent
+      ? this.extractRelayHintsFromComment(commentEvent, undefined, coordinate)
+      : [];
+
+    // Get author's outbox relays
+    let authorOutbox: string[] = [];
+    try {
+      const relayListEvent = await firstValueFrom(
+        eventStore.replaceable(10002, pubkey, ""),
+        { defaultValue: undefined },
+      );
+      if (relayListEvent) {
+        authorOutbox = getOutboxes(relayListEvent);
+      }
+    } catch {
+      // Ignore errors fetching relay list
+    }
+
+    // Merge all hints (prioritize pointer hints, then comment hints, then author outbox)
+    const allHints = mergeRelaySets(
+      pointerHints,
+      commentHints,
+      authorOutbox.slice(0, 3), // Limit outbox to 3 relays
+      additionalHints,
+    );
+
     const relays =
-      relayHints.length > 0 ? relayHints : await this.getDefaultRelays();
+      allHints.length > 0 ? allHints : await this.getDefaultRelays();
 
     const filter: Filter = {
       kinds: [kind],